
Madre de Dios Region Vacation Packages
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Your Madre de Dios Region Vacation
Choose one of our vacation packages to Madre de Dios Region and wander wherever your adventurous soul takes you. Hiking and nature are just a couple of the things you can look forward to in this wonderful destination. Start your trip to Madre de Dios Region by spending a few nights in Tambopata, one of the top cities here. Expedia has hotels, flights and all your other travel needs to help you curate your very own customized Madre de Dios Region vacation today.
Where to stay in Madre de Dios Region
Chapajal
Madre de Dios Region Hotel Deals

IKAM Riverview Amazon Lodge - Asociado Casa Andina
"Pros: the grounds were beautiful, comfy bed, AC. Cons: no services nearby, must take a taxi into town to get anywhere. Pricing of meals and activities not inclusive so you pay a lot at check out. There is nowhere else to eat so you have to eat there. The dinners were great, free breakfast was not ..."
Reviewed on Jun 9, 2026

Libelula Hotel
"Good hotel! Recommend to book"
Reviewed on May 14, 2026

Ecolucerna Lodge Tambopata
"we had a beautiful time at the lodge. the staff makes this property amazing! the food was so good, they are organized and friendly. same as other reviewers as no hot water, but its so hot out that a cool shower feels amazing!"
Reviewed on Oct 29, 2025
Frequently asked questions
Discover the most popular places to visit in Madre de Dios Region
Manu National Park
Explore the great outdoors at Manu National Park, a lovely green space in Manu.
Collpa La Cachuela
You can take time to visit Collpa La Cachuela during your travels to Puerto Maldonado. Wander the riverfront and forest while you're in the area.
What to do in Madre de Dios Region

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

Puerto Maldonado: Sandoval Lake Full-Day Trip with Canoeing








